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CASE REPORT
Year : 2014  |  Volume : 1  |  Issue : 2  |  Page : 112-113

IUI in hypogonadotropic hypogonadism: Do not give up


1 Consultant and ART Specialist, ART Centre, Army Hospital (R&R), Delhi Cantt, New Delhi, India
2 HOD and ART Specialist, ART Centre, Army Hospital (R&R), Delhi Cantt, New Delhi, India

Correspondence Address:
Dr. Seema Rai
Consultant and ART Specialist, ART Centre, Army Hospital (R&R), Delhi Cantt, New Delhi - 110010
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2394-4285.162788

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Ovulation is dependent on the presence of a functioning hypothalamic-pituitary-ovarian (HPO) axis. Estimates of chronic anovulation rates range from 6-15% of women during the reproductive years.Potential causes of anovulation are PCOS, hyperprolactinemia,thyroid dysfunction, stress etc. Idiopathic hypogonadotropichypogonadism (IHH) is rare cause of anovulation. Idiopathic hypogonadotropichypogonadism (IHH) is a collection of genetic mutations that result in delay of puberty, infertility, and low gonadotropins.Women with IHH have hypoestrogenism, amenorrhea, and low gonadotropin levels. Ovulation induction is the method for treating anovulatory infertility. For patients with hypogonadotrophichypogonadism, the treatment involves administration of both FSH and LH, while HCG is injected for follicle rupture. Such patients need high dosage and longer duration of stimulation than other patients.


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