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ORIGINAL ARTICLE
Year : 2017  |  Volume : 4  |  Issue : 2  |  Page : 87-92

Retrospective analysis of GnRH antagonist cycles to assess ovarian reserve parameters as the predictors of clinical pregnancy


IVF and Reproductive Medicine, Max Multispeciality Hospital, Delhi, India

Correspondence Address:
Dr. Surveen Ghumman
B 517 New Friends Colony, Delhi 110025
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/fsr.fsr_14_18

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Aim: The present study aims to correlate AMH and AFC, with the number of retrieved oocytes , number of Grade1 embryos and clinical pregnancy in IVF/ICSI cycles stimulated with GnRH-antagonist protocol. Materials and Methods: 49 women who underwent grade 1 cleavage stage fresh embryo transfer from May to August 2017 were included. Primary end point was clinical pregnancy i.e. positive cardiac activity at 6 weeks. Pearson’s correlation coefficient was calculated and stepwise regression analysis was done to identify the best predictor. Results: Out of 49 patients 21 patients (42.9%) were pregnant. Serum AMH and AFC significantly correlated with the number of oocytes obtained (P=0.00, P=0.00). A positive correlation of serum AMH and AFC was seen with number of grade 1 embryos , but it was not significant. AFC had a stronger correlation with number of oocytes and grade 1 embryos than AMH . Stepwise regression analysis indicated that number of grade 1 embryos was an independent predictor for clinical pregnancy (P= 0.19) with an overall accuracy of 63%. Conclusion: Counselling of patients regarding outcome of IVF cycle should be based on the number of grade1 embryos.


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