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REVIEW ARTICLE
Year : 2019  |  Volume : 6  |  Issue : 1  |  Page : 10-15

Effect of modifiable risk factors on semen parameters


1 IVF & Reproductive Biology Centre, Maulana Azad Medical College, Del, India
2 Department of Urology, VMMC & Safdarjung Hospital, New Delhi, India
3 IVF & Reproductive Biology Centre, Maulana Azad Medical College, Delhi, India

Correspondence Address:
Saumya Prasad
IVF & Reproductive Biology Centre, Maulana Azad Medical College, Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/fsr.fsr_27_19

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Objective: This article examines the potential effects of lifestyle factors on male reproductive health. Evidence of a global decline in human sperm quality over recent decades has been accumulating. Environmental, occupational and modifiable lifestyle factors may contribute to this decline. This review focuses on key lifestyles factors such as diet, caffeine intake, tobacco chewing and alcohol intake. Method: A comprehensive literature search was performed to identify the major lifestyle factors associated with male infertility and semen quality. Database searches were limited to reports published in English only. Results: A prudent diet consists of high intake of fish, fruit, vegetables and legumes. Fat in diet is also as essential as other component of the diet. Although largely the evidence is observation based, evidence appears to support an approach of moderation carbohydrate and fats with better semen parameters. A good intake of antioxidants in diet and supplement correlates with higher sperm numbers and motility. The other very important modifiable factors are tobacco chewing, alcohol and caffeine intake. Nicotine in tobacco is found to suppress sperm progressive motility; it also reduces the percentage of viable spermatozoa and increases the altered chromatin compactness. Alcohol consumption leads to increased testosterone level due to change in oxidation metabolism of steroids in liver. Alcohol oxidation increases the Nicotinamide adenine dinucleotide (NAD) ratio which causes the re-dox state in favour of conversion of androstenedione into the reduced steroids testosterone and oestradiol. Caffeine intake has been associated with sperm DNA defects, aneuploidy and DNA breaks. Conclusion: The major lifestyle factors discussed in the present review are the potential issues that can possibly impair male infertility. However, their negative impact can be overcome by behavioural modification and better lifestyle changes.


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